Major Highways

These major highways serve southwest Indiana:

  • Interstate 64 – East-west access to Louisville, Kentucky, and St. Louis Missouri; plus Interstate connections in all directions
  • Interstate 69 – Connects Interstate 64 and Indiana 57 to U.S. 41 near Evansville, Indiana and presently extends to Indianapolis, Indiana.
  • U.S. 41 – 4-lane access to Chicago, Illinois, and Miami, Florida; connects to the Kentucky Parkway System; connects to Interstate 24 (Nashville, Tennessee, and Atlanta, Georgia)
  • Indiana 62 – East-west access across southern Indiana
  • Indiana 66 – Scenic east-west access along the Ohio River
  • Indiana 57 – Access to the areas northeast of the region, including part of the proposed interstate route, connecting Indiana to Canada

Download a map of the major highways in Southwest Indiana

Major Highway Improvement Projects

  • Interstate 69 – Currently under construction
    • Presently extends to Indianapolis, Indiana, to Port Huron, Michigan, and the Canadian border
    • Will soon connect Evansville, Indiana, to Indianapolis, Indiana
    • To the south of Evansville, Indiana, the proposed Interstate route extends to the Mexican border

Download a map of the Interstate 69 project (PDF)

Freight Rail

These freight rail companies offer service in Southwest Indiana:

Download Indiana Freight Rail Map (PDF)

River Ports

Several area ports offer rail-to-water transload facilities, extensive storage areas, and a wide range of services:

View Video of Ports of Indiana – Mt. Vernon

Air Travel

Evansville Regional Airport offers multiple daily flights:

  • American Eagle to Chicago O’Hare International Airport (ORD)
  • American Eagle to Dallas/Fort Worth International Airport (DFW)
  • Delta Connection to Hartsfield-Jackson Atlanta International Airport (ATL)
  • Delta Connection to Detroit Metropolitan Wayne County Airport (DTW)
  • Delta and American Eagle Connections to Charlotte Douglas International Airport (CLT)

See the regular flight schedule.

Private flight service is available through Tri-State Aero.

Air Freight

A number of companies provide air freight services for southwest Indiana. View air freight directory.